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The reason for the improve towards the quinolone substructure is mysterious, but it could are located to generally be an acceptable alternative for your naphthoyl moiety that may be now controlled by US scheduling legislation.[81]
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Most artificial cannabinoids are agonists from the cannabinoid receptors. They are meant to be just like THC,[9] the organic cannabinoid With all the strongest binding affinity for the CB1 receptor, which can be associated with the psychoactive effects or "high" of marijuana.[ten] These synthetic analogs usually have better binding affinity and increased potency to the CB1 receptors.
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